this is really interesting stuff....

it definitely makes you have to think

http://www.msnbc.msn.com/id/21134540/vp/31686327#31686327

More to think about, human genome sequencing: the first genome cost about $3 billion and took hundreds of people a decade to assemble (announced in YR2000), now the technology is automated, takes about a week and costs is approaching $1000.

http://www.helicosbio.com/Technology/TrueSingleMoleculeSequencing/tSMStradeHowItWorks/tabid/162/Default.aspx

(my area of expertise)

http://www.youtube.com/watch?v=uf6EGvl7nJo

i watched your video

ok, so you have the $1000 dollar G-Nome
now what?

explain in Laymans terms what it means...
enough so that Curly
from the three stooges could understand :hihi:

Many diseases have a root cause at the genetic level: cancer(s), Alzheimer's, hypertension, diabetes, etc. Although it will still take years to understand much of the genetic signatures for these diseases, once understood it (might) be possible to start early treatment to manage the disease or even prevent it from occurring (fix the bad gene with a good gene, e use of stem cells). Many drugs appear to work on specific gene signatures and don't work on others. Drug companies today archive patient samples in order to understand the gene signatures for patients that the drug is effective/not effective/lethal. Analysis of these samples is by in large waiting for a high throughput, INEXPENSIVE sequencing technology to allow the processing of these samples. If a clinical trial involves a 1000 people, and analysis cost $1000 or more/person these trials become prohibitively expensive. Drugs that fail clinical trials in the general population are found which work on a subset and can be rescued.

How'd I do Curly?

How'd I do Curly?

Most excellent ...i followed the logic....

your method utilizes the mechanism already in place but customizes the drug to work with the gene rather than utilizing or incorporating a foreign artificial body to do the work as represented by nanotechnology.

If you are interested in genome sequencing and have 52 minutes to spare, here is an interesting interview:

http://www.youtube.com/watch?v=3E25jgPgmzk&feature=haxa_popt1cus14

It might take a Mo vs Curly to understand although I think most of the discussion meant for a TV audience is at a basic level.