Typically to totally clean spyware from a machine I will use
Ad Aware
Spybot
CWS Shredder
Hijack This
LSP Fix
and either TDS3 or Housecall - sometimes both.
Then you need to check the small things like startup and msconfig and clear temp internet files etc..
Spyware is a nasty thing... But it does have its purposes.. I had a customer a few months ago that couldnt install "The Sims" it ended up he was so clogged with spyware it wouldnt allow it till it was clean.. He was almost saved.
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