I just fixed another pc with Spysweeper.
It was reel slow, pop-ups galore and couldn't even access internet. I ran Adaware and Spybot but didn't solve problem.
I went and bought Spysweeper($19.99 at CompUSA) and it removed over 8000 items. Some wouldn't deleate the first time so I had to run it again in Safe mode(John R's advice).
PC works like a champ again.
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