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Great Stuff -- the spray-in foam insulation -- fills holes well and also poisons the rodents if they chew it, I've heard.
The plastic easy set traps rule, except when they don't make a killing snap and you hear the mouse screams (who knew they could do that?) and when the noise subsides and you check the trap, it and the mouse are gone.
D-Con works okay for me. No "smelly mouse, smelly mouse, where in the wall are you?" for me yet. But I did have one stumble out from behind the wood box one nite and keel over right in front of me while I was watching TV. I put a box on top of it, added a pair of boots for good measure, and waited for RRC to come home and work his coroner magic.
Found one all rigor mortis in the bag of recycling once. Woke up one morning to peanut butter cookies that I had left out strewn across the floor. But the sketchiest situation was waking up in the morning with one all warm and furry nuzzled against my face and having it run down my leg and out the bed to hide. I don't think my feet touched the bedroom floor.
They love piles of clothes, sheets, towels, etc. Stuffed animals, too. Rarely-used furniture. Newspaper and insulation are good for chewing to build nests.
My advice is to cover all the holes you can, inside and out, and use any method possible to get rid of the little beasts. Shake out, pick up, and if possible, put in a container, any loose, comfy, nesty-type items. Even when you think they're gone, keep a trap or two set. We just got one Friday morning over by the...go figure...bag of birdseed.
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