I too use the Ande mono for leaders.I keep it simple,50lb around rocks and rocky bottoms and 30lb everywhere else.For knots I use a palomar for the 30 and an improved clinch for the 50.A 50yd spool of each is just about enough for a season's worth of leaders for me.
To make knot tying a little easier I use an "extra hand".Basically a screw eye buried into a board which is clamped down to a work bench. On the screw eye is a heavy duty split-ring.I just attach the swivel or the snap to the split-ring and now have both hands free to tie and pull with.This will work with the palomar too just tie the form of the knot before attaching to the ring
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