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I had soaked some of the tip parts in acetone once before and it actually didn't do much to take the paint off. I figured it would eat right through it but it didn't. I do know that Acetone will eat through plastic like there's no tomorrow though, so if there are any plastic pieces inside you can probably say goodbye to them.
I do the same as Chris and send a Pipecleaner through it to clean it out. Seems to work pretty good.
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