traffic is definitely key, scott.
if you can get past allentown, pa in the wee hours of the morning then you'll be okay. past 7:30 a.m. however ...
otherwise ... you can take I-84 through CT (lots of congestion in Hartford and Waterbury!) and NY (smooth sailing once you're over the bridge) and then cut over to I-80 thru Scranton, PA (nice place for a coffee pitstop).