I've been lucky that I don't get spined......of course I don't catch fish either, but that's not important.
Seriously, if you remove the spine, flush the puncture with water or even just squeeze it so that it bleeds a little, you can clean out most infectious material.
Most cases of infection and blood poisoning occur when the wound is not treated properly from the start.
I haven't had the fortune of having a large hook find its mark on me, but I did have a size 8 treble hook find my pinky this spring.
Damn, that hook was sharp. Buried up to the bend!
I did a little field surgery (pliers and quick yank) and I was free!
I did remember to press the hook down to allow the barb to come out more easily, and I pack a first aid kit and after a couple of bandaids and some neosporin I was good to go.
Isn't it funny how we remember how to do things, like remove a hook, even if it hasn't been needed in decades?