The 4000 and the 4500 are the same except for the spool's capacity, and I believe the spools are interchangeable.
Same with the 5000 and 6000, although there is a high speed retrieve version of the 6000.
To me, buying the 5000 makes no sense. If two reels weigh the same, and cost the same, buy the one that holds more line
The 4000 and 4500 weigh about 20 oz, the 5000 and 6000 weigh 29oz. That seems like a lot of reel for a 1322, but I'd have to see how the balance is before saying it's a bad match.
However--it's only 4 oz heavier than a 25 oz Emblem Pro and that reel is used extensively by Canal guys on 1322s.